Cambridge Healthtech Institute’s 2nd Annual
Next-Generation Analytical Methods
New Technologies and Enhancements to Enable the Characterization of Complex Biotherapeutics
August 20-21, 2025
The Next-Generation Analytical Methods conference presents a comprehensive exploration of how modern analytical technologies are evolving to meet the demands of new therapeutic modalities. Discussions will encompass characterization of complex biologics, including co-formulations and fusion proteins, as well as innovative approaches for genomic integrity analysis and CRISPR applications in cell therapy. Participants will learn about the growing role of NGS, the future of MS technologies, and how digital tools such as AI and digital twins are redefining analytics. The integration of emerging bioanalysis techniques like microfluidics and omics will further illustrate the capabilities shaping the next era of therapeutic development.
Coverage will include, but is not limited to:
New Methods and Method Selection for Emerging Modalities
- Bi/tri/multi-specifics
- Co-formulations
- Fusion proteins
- Novel conjugations
- Oligos
- Platform and data strategies for new modalities
New Methods for Gene and Cell Therapies
- CQAs and control strategies for genetic medicines
- CRISPR/Cas9 technologies for CT purity analysis
- Higher throughput liquid handlers
- Methods to characterize genomic integrity
- Real-time measurement technologies for AAV production analytics
NGS for Characterization Applications
- Assay development for NGS applications
- Best practices for implementing an in-house NGS capability
- Platform selection
Use Cases of Digitalization and ML/AI for Analytical Methods
- AI to simplify and expand analysis of MS data
- Analytical impacts of digital twins and in silico process models
- Best practices for using collaborative AI platforms
- Upskilling and training initiatives to support development of bench scientists
Expanding the Application of MS Technologies
- Emerging MS features and formats
- MAM applications for new modalities
The Future of Bioanalysis in R&D
- Omics technologies
- Sequencing technologies
- Single cell/microfluidic analysis
- Workcells for complex analyses
The deadline for priority consideration is January 27, 2025.
All proposals are subject to review by session chairpersons and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.
Opportunities for Participation: