Cambridge Healthtech Institute’s 12th Annual

Optimizing Cell Line Development

Enhancing Expression

August 27-28, 2020


As the biopharma field becomes increasingly more complex, engineering cell lines continues to be a foundation for developing biologics. This foundation draws from emerging research and breakthrough strategies to achieve cell lines that accomplish project goals quickly and inexpensively. The Optimizing Cell Line Development conference brings together experts who will share how to best optimize codons, construct vectors, and select and engineer clones and host systems, while maintaining stability and consistency. The conference will also focus on automation, high-throughput, genomic research, glycoengineering, systems biology, and pathway delineation.


Coverage will include, but is not limited to:


  • Gene expression/expression levels
  • Genomic research
  • Glycoengineering
  • Trends in industrial cell line development, such as CRISPR
  • Codon optimization
  • Vector construction
  • Clone selection & optimization
  • Host system selection & use
  • Cell line selection
  • Cell line attributes
  • High producer cell lines/industrial use
  • Synthetic biology
  • Regulatory perspectives on new technologies
  • Systems biology
  • Metabolomics
  • Hurdles for introducing new technologies
  • Sequencing the CHO genome
  • Transcriptomic data
  • Predictive modeling
  • Identifying the best hosts
  • Understanding hosts to control phenotypes
  • Engineering hosts
  • Designing a cell line for biosimilars
  • Arrays/microarrays
  • Process conditions & robustness
  • Developing new cell lines
  • Cell growth
  • Stability
  • Productivity
  • Reproducibility
  • Quality
  • Scalability
  • Cell line serviceability through late-stage product development
  • Protocols & case studies


If you would like to submit a proposal to give a presentation at this meeting, please click here.


The deadline for priority consideration is February 21, 2020.


All proposals are subject to review by session chairperson and/or the Scientific Advisory Committee to ensure the overall quality of the conference program. Additionally, as per Cambridge Healthtech Institute’s policy, a select number of vendors and consultants who provide products and services will be offered opportunities for podium presentation slots based on a variety of Corporate Sponsorships.


For more details on the conference, please contact:
Mary Ruberry
Senior Conference Director
Cambridge Healthtech Institute

Phone: (+1) 781-972-5421


For partnering and sponsorship information, please contact:

Companies A-K
Sherry Johnson
Senior Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-1359

Companies L-Z
Carolyn Cooke
Manager, Business Development
Cambridge Healthtech Institute
Phone: (+1) 781-972-5412

Premier Sponsors: