This stream brings together Analytical Intelligence and Next Generation Methods to highlight the intersection of automation, predictive analytics, and emerging technologies in biotherapeutic development. Sessions explore miniaturized and end-to-end automated workflows, mass spectrometry innovations including proteoform-resolved and single-particle approaches, and advanced MAM and single-cell platforms. Structure–function analyses using AI/ML, cryoEM, and advanced microscopy are showcased for their role in CQA assessment, risk evaluation, and method development. The stream emphasizes predictive modeling for formulation, stability, and analytical target profile development, while addressing the practical challenges of digitization, workflow integration, and regulatory requirements to advance efficiency and insight across modern analytical pipelines. 

Programs Include: