Andrew Sinclair Offers Insight on Optimizing Manufacturing and Operations, Part 2

February 3, 2026

Picking up from their previous conversation on Bioprocessing Unfiltered, Andrew Sinclair, president and founder of BioPharm Services Ltd., and host William Whitford, founder of Oamaru BioSystems, discuss improving manufacturing efficiency, including process mass intensity and setting up parameters, and more on Sinclair’s long career and valuable experiences in the industry. Sinclair also shares advice on helping someone who cannot meet parameters, how to navigate new profusions, and default values that can help others with their processes.

GUEST BIO

Andrew Sinclair, MSc, CEng, FIChemE, FREng, President & Founder, BioPharm Services Ltd.
Andrew has over 30 years’ design and operational experience in the biopharmaceutical industry, with direct responsibility for manufacturing, logistics, maintenance and capital program management. He has developed BioPharm Services into a leading provider of bioprocess modelling and knowledge management tools that support bioprocess innovation. The focus of his work is on understanding the impact of innovative technologies on biomanufacturing with a focus on single-use systems and continuous processing. Prior to BioPharm Services, Andrew was director of engineering and logistics at Lonza Biologics and holds a master’s degree in biochemical engineering from UCL. He was a finalist in “The Manufacturing Processing Thought Leader of the Decade” category at the 2012 BioProcess International Awards and in 2014 was appointed a Fellow of the Royal Academy of Engineering in the UK.

HOST BIO

William Whitford, Founder, Oamaru BioSystems
Bill is founder of Oamaru BioSystems with over 20 years’ experience in biotechnology product and process development. He now publishes oral papers, print articles, and book chapters on such topics as ATMP process intensification, AI/ML tools, and net positive building economy in biomanufacturing. His work has been acknowledged in the 2022 APEX Award for Publication Excellence in the Technical & Technology Writing category and the 2023 ISPE Roger F. Sherwood Article of the Year award. He currently enjoys serving on such committees as the BioProcess International Editorial Advisory Board, and the chair of the 3SMAGNET Intersectoral Advisory Board. Bill has an h-index of 18 and an i10 index of 37.

TRANSCRIPT

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